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Agronomic biofortification with selenium and zinc in tomato plants ( Solanum lycopersicum L.) and their effects on nutrient content and crop production

The in vitro cell-based mechanistic studies have reported that PNS can upregulate the angiogenic capacity of endothelial progenitor cells by activating the Wnt/-catenin signaling pathway and synergistically regulate the HIF1-/VEGFA/VEGFR2 signaling axis to promote angiogenesis, thereby improving cerebral microcirculation disorders (Zhu et al., 2021