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These signs suggest you need immediate electrolyte assessment: New or worsening heart palpitations, chest discomfort, or skipped beats Severe muscle weakness where you cant grip objects or stand Confusion, disorientation, or altered mental status Seizures Difficulty breathing (may indicate fluid overload or severe metabolic acidosis) Severe persistent cramps, numbness, or tingling that dont resolve Signs of shock including very low blood pressure, rapid weak pulse, cold clammy skin, or major brain-related changes such as loss of consciousness require immediate emergency services

[7] [9] Caution is advised in individuals with renal insufficiency or those on dialysis, as impaired clearance may increase the risk of accumulation and toxicity

SeNPs have a wide variety of biological applications, have been developed for dietary supplements as well as therapeutic agents and do not exhibit noticeable side efects in cancer

doi: 10.1016/B978-0-12-819587-1.00003-3 315 TurnbaughP