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Of note, Cef has been shown not only to induce EAAT2 expression but also to activate the transcription factor Nrf2 (Lewerenz et al., 2009), which induces the transcription of a plethora of genes involved in cytoprotection and antioxidant defense (Kensler et al., 2007)

Baililai Biotechnology Co., Ltd., Shanghai, China) were used to determine the activity of related enzymes

( E ) Dissemination gene panel (n = 5 genes) identified in Hosseini et al, 2018 from ( D ) were analyzed for impact on overall survival in pancreatic cancer (KMPlot)

High concentrations of AuNRs have been reported to impair antioxidant enzyme activity in bladder cancer cells, thereby increasing oxidative stress 73