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Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation

Med Oncol 31:889 Al-Eitan LN, Rababah DM, Alghamdi MA, Khasawneh RH (2019) Association of GSTM1 , GSTT1 and GSTP1 polymorphisms with breast cancer among Jordanian Women

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Concurrently, the failure of energy-dependent Na/K-ATPase and calcium pumps leads to sodium and calcium influx, causing cellular swelling and exacerbating calcium overload, while also activating proteases and phospholipases, ultimately inducing necrotic death characterized by membrane rupture [40, 45, 47]