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ANO1: central role and clinical significance in non-neoplastic and neoplastic diseases

Treat poorly documented capsules as the bigger near-term risk, not the compound itself

Water for injection systems (WFI) Purified Water Systems "The significance of microorganisms in non-sterile pharmaceutical products should be evaluated in terms of the use of the product, the nature of the product, and the potential harm to the user." (USP Microbiological Attributes Chapter )There are no clear microbiological specifications for purified water systems

Results: We observed a proband (III-7) with an abnormality in the cerebral white matter, apnoea, and microcephaly