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Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients

The mouse anti-GAPDH antibody (ab8245, 6C5, GR3275542-1), mouse anti-GGT antibody (ab55138, 1F9, GR1017756-3), rabbit anti-Calreticulin antibody (ab2907, GR3426057-2), rat anti-CD8 antibody (ab25478, 53-6.7, GR3181210-4), goat anti-rabbit IgG H&L (HRP) (ab6721), goat anti-rabbit IgG H&L (Alexa Fluor 488) (ab150077), and goat anti-rabbit IgG H&L (Alexa Fluor 555) (ab150078) were purchased from Abcam (Shanghai, China)

Third, based on the data presented in this paper, HPL exhibited the potential to restore Anpep expression in the glutathione metabolism pathway and turnover-induced metabolite shift, which reflect the powerful effect of HPL on glutathione redox stress