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Zhang, S., et al

Heme-Mediated TLR4-Dependent EC Activation (Adhesion Molecules and Barrier Function) ECs respond to a variety of inflammatory stimuli e.g., IL-1, tumor necrosis factor (TNF-), lipopolysaccharid (LPS) by upregulating the expression of cellular adhesion molecules including intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E selectin (74, 75)

FIGURE 7 3.7 Catalase Response Unlike any other antioxidant enzymes evaluated in this study, the CAT response for non-exposed groups 1 to 3 was distinctively different