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Wu, J., Ocampo, A

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In the context of DCM, however, compromised lysosomal acidification and diminished hydrolase activity impede the degradation of autophagosomes, resulting in their progressive accumulation ( Various experimental models have demonstrated that in obesity and diabetes, cardiomyocytes show significant downregulation of lysosomal structural proteins and hydrolases

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Expert Rev Gastroenterol Hepatol 2021, 15 (7), 759769

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For dysphagia, that splits two ways

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