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Miyata S, Kawashima Y, Sakai M, Matsubayashi M, Motoki K, Miyajima Y, et al

remediation of oxidative stress resulting from iron deposition and mitochondrial dysfunction

Dispersed islet cells from high-fat diet (HFD)-fed hIAPP Tg/0 and hIAPP 0/0 littermates on an F1 C57BL/6J FVB/NJ background were pooled (five mice per sample) and sorted into CD45 + and CD45 fractions via BD FACS ARIA II (BD Biosciences), and reconstituted to a final composition of 30% CD45 cells and 70% CD45 + cells