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Patients presenting with post-inflammatory hyperpigmentation from acne or sun damage, which is especially prevalent in South Floridas Fitzpatrick III through VI population, see meaningful tone evenness improvements alongside texture changes

No validated human protocols exist

They also inhibit neural cell necrosis and induce the proliferation of astrocytes

used a repository of transcriptional responses to compounds, the Connectivity Map (cMap) [60], and MANTRA software ( to explore networks of compounds producing similar transcriptional responses