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Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy

doi: 10.1016/j.lfs.2021.119935 70 UrsuONSauterMEttischerNKandolfRKlingelK

However, when present in excess, it contributes to the development of fatty deposits in the arteries, which can restrict blood flow and lead to serious health issues such as heart attacks and ischemic strokes [1][2]