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irritans could be a biomarker for oxidative stress induced by zinc ions

*Correspondence: Wenjuan He, [email protected] Zhou, [email protected] These authors have contributed equally to this work ORCID: Hao Zhou, orcid.org/0000-0002-8411-1589 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

For prostanoid generation, both COX-1, which is constitutively expressed by most cells, and COX-2, an inducible isoform upregulated by inflammatory mediators such as lipopolysaccharide, IL-1, IL-6, or tumor necrosis factor- (TNF-), convert AA into prostaglandin endoperoxides (PGs), such as prostaglandin G 2 (PGG 2 ) (Ramsay et al., 2003

Das D, Pham HTT, Lee S, Noh I (2019) Fabrication of alginate-based stimuli-responsive, non-cytotoxic, terpolymric semi-IPN hydrogel as a carrier for controlled release of bovine albumin serum and 5-amino salicylic acid