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Description

Ann Allergy Asthma Immunol 2006

We observed that RSL3 treatment significantly increased the accumulation of labile iron, ROS and lipid peroxides and accompanied by the reduction or disappearance of mitochondrial cristae in prostate cells, while GPX4 decreased

Additional well-designed clinical studies are required to determine the long-term biological significance and potential translational applications of NNMT inhibition in humans