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The third potential key role in the development of chronic inflammation that leads to airway remodeling in asthma and obesity is the role of inflammasome

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Moreover, signaling pathways commonly associated with stemness, notably the Notch, Hedgehog, and PI3K/AKT/mTOR pathways, intersect with metabolic regulators, forming feedback loops that tightly control energy production, biosynthesis, and cell fate decisions

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