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In these studies, obese participants received 2.5 mg tirzepatide SC QWK for four weeks, followed by four weeks of 2.5 mg tirzepatide SC QWK and/or 1.25 mg bremelanotide SC QD, and finally four additional weeks without any treatment

[25] Pinero J, Ramirez-Anguita JM, Sauch-Pitarch J, et al

However, serum levels of estrogen and testosterone did not differ substantially between the two groups

HaCaT cells (keratinocyte cell line, Deutsches Krebsforschungszentrum) are seeded (8000 cells/well, 4 wells per condition) in 96-well plates for 24 hours at 37 C