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Figure 9

Furthermore, mtDNA activates Z-DNA binding protein 1 (ZBP1), mediating PANoptosis in endothelial cells [21]

Genetic deletion of CD36 or pharmacological inhibition of ferroptosis in CD8+ T cells can restore their cytotoxicity and synergize with anti-PD-1 immunotherapy [41]

(111) discovered resveratrols role in activating the SIRT1/AMPK pathway, which phosphorylates AMPK to inhibit intracellular autophagy via downregulation of Beclin-1 and upregulation of p62, thereby promoting GC growth and proliferation in PCOS rats