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Gallbladder disease (including gallstones and cholecystitis) has been reported with GLP-1 receptor agonists, particularly with substantial weight loss

With regard to the amelioration of hyperglycemia in fat-transplanted Insr P1195L/ +/HFD mice, it is unclear whether the improved glucose uptake into the transplant may play a major role, as WAT has been reported to play a minor role in glucose uptake in rodents 20