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Orders are dispatched quickly and typically arrive to U.S.-based researchers in 2-3 days

Fresh all-trans retinoic acid (Sigma-Aldrich, Saint Louis, MO) was added to the culture medium at a final concentration of 10 ng/mL

The sample included adults ages 18 to 60+, with representation from all major U.S

The study confirmed FOXO4-DRI was effective across senescent cells generated by different methods (irradiation, doxorubicin, and replication stress), and documented that pre-treatment with FOXO4-DRI attenuated the dedifferentiation of chondrocytes during in vitro expansion establishing it as a valuable tool for research into senescent cell biology in cartilage and musculoskeletal models