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Mitochondrial ROS and mitochondria-targeted antioxidants in the aged heart

Moreover, PARP inhibition reportedly prevented the recruitment of FET proteins, while PARG inhibition prolonged the presence of FET proteins in DNA damage sites in vitro, which was also observed in hnRNP A1 and TDP-43 131

Vascular leak syndrome is caused by the production of IL-6, which activates the coagulation and complement pathways, resulting in the most conspicuous manifestations of cytokine release syndrome (Hunter and Jones 2015