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In addition, GA pretreatment ameliorated doxorubicin (Dox) -induced hepatotoxicity and oxidative stress

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Binding of OxLDL to LOX-1 promotes the production of O - and H 2 O 2 , as well as activation of NF-kB via p38 MAP kinase signaling pathway [178, 179], thus eliciting an inflammation in the endothelial cells