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C-ABL Inhibitors So far trials with Abelson murine leukaemia viral oncogene homologue 1 (c-ABL) kinase inhibitors have not been successful with two randomised placebo-controlled trials with nilitonib and vodobatinib both failing to detect efficacy signals on the change from baseline of MDS-UPDRS part III scores [203]

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42 Chronic kidney disease (CKD) In patients with predialysis CKD, reduction of serum aminotransferase level has been reported to be proportional to the progression of the disease

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