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When nausea is part of the picture, anti-nausea medications like Zofran can be added

99 Folate also enhances regeneration of BH 4 from inactive BH 2 by stimulating dihydrofolate reductase and it chemically stabilizes BH 4

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Furthermore, SFN orchestrates a multi-pronged assault on cancer cells by promoting the acetylation of non-histone proteins such as p53, and synergistically activating critical pathways including cell cycle arrest, apoptosis, and sensitization to other therapeutic agents like TRAIL, which is particularly promising for targeting therapy-resistant cases (66)