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Classification of MASLD, MetALD, ALD and no SLD by the algorithm also showed high correlation with chart review, with a kappa of 0.87 (95% CI 0.82-0.91), and identified 436,974 (53.4%) of participants to have SLD, compared to ICD 9/10 codes in only 23,218 (2.8%) patients

Factors under investigation include: Peak GH secretion Duration of pulses Receptor sensitivity Hormonal feedback Interaction with GHRH analogs It is worth noting that the magnitude of these responses depends heavily on the methodology used and the animal models involved

95 IshidaT.HattoriS.SanoR.InoueK.ShiranoY.HayashiH.et al (2007)