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Science 292:24992501 Carlezon WA Jr, Thomas MJ (2009) Biological substrates of reward and aversion: a nucleus accumbens activity hypothesis

Abbreviations ABTS: 2,2-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) b.w: Body weight COX: Cyclooxygenase DPPH: 2,2-Diphenyl-1-picrylhydrazyl EC 50 : The half maximal effective concentration ED 50 : Median effective dose IC 50 : The half maximal inhibitory concentration IL: Interleukin iNOS: Inducible nitric oxide synthase LC-HRMS: Liquid chromatography-high resolution mass spectrometry LDL-C: Low-density lipoprotein cholesterol LPS: Lipopolysaccharide MAPK: Mitogen-activated protein kinase MIC: Minimum inhibitory concentration NF-B: Nuclear factor kappa B NO: Nitric oxide NOAEL: No-observed-adverse-effect-level Nrf2: Nuclear factor erythroid 2-related factor 2 ROS: Reactive oxygen species SB: Sea buckthorn TEAC: Trolox equivalent antioxidant capacity TGF-: Transforming growth factor beta TNF-: Tumour necrosis factor alpha References Abdullahzadeh M, Shafiee S (2021) To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second-degree burns: A randomized triple-blind clinical trial

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As a result the patient is left feeling sluggish and run down