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Moore and June, 2020

They measured subjective sleep quality more than objective sleep quality They subjectively estimated tiredness Sleep structure was not fully characterized by polysomnography in all studies Data analysis suggested some observed changes were due to issues with the placebo group What is promising about these findings is that statistically significant effects were found in such small sample sizes

Mitochondrial dysfunction in PAIS As mitochondria constitute the key ATP power plant, i.e., the energy provider in our cells, the importance of their dysfunction in PAIS and other diseases characterized by a hypometabolic state and fatigue could well be crucial