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Acc Chem Res 14:393400 Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, Miwa S, Pakay JL, Parker N (2004) Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

The application of cannabinoids may help since they directly act on astrocytes to diminish cytokine release (Sheng et al., 2005

Figure 2 2.2 Lipid metabolism and antioxidant systems regulate ferroptosis Lipid synthesis and catabolism directly or indirectly influence lipid peroxidation in ferroptosis

(iii) the branched-chain -ketoacid dehydrogenase complex that is involved in the decarboxylation of ketoacids in the catabolic pathway of the branched-chain amino acids, namely leucine, isoleucine, and valine