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Evaluation of the effects of dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on hepatic steatosis and fibrosis using transient elastography in patients with type 2 diabetes and non-alcoholic fatty liver disease

The LC 50 values for MDA-T68 and MDA-T32 cells were ~ 0.05 M and 0.2 M, respectively

Given that cytoplasmic mislocalization and aggregate formation of FUS are common in neurons in FUS-associated proteinopathies, it is likely that regulation of the FUS glutathionylation-mediated stress-mitigating mechanism by GSTOs may also underlie other ALS cases and related diseases, including FTD