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However, there are dynamic scaffold-based 3D models used to study flow shear stress, such as polydimethylsiloxane (PDMS) only models, and others that combine the hydrogel cell culturing techniques with more complex microfluidic systems, namely PDMS-derived, PDMS-hydrogel hybrids, or pure hydrogel models [259]

5 In contrast, higher-risk MDS is associated with a significant risk of progression to AML and shorter survival, and treatment aims to modify the disease course, with options including hypomethylating agents (HMAs) such as azacitidine or decitabine, allo-SCT and, less frequently, chemotherapy

Intermittent infusion may be used when there are concerns about the stability of medicine in solution for long periods of time (as is common with continuous infusions), or to enable the administration of medicines which would be incompatible if administered at the same time in the same IV line, for example vancomycin

10.1155/2022/2133705 44 MaoZ.ZhongK.LiuX.ZengX