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The attached water molecules were diminished

The role of Nrf2 in regulating ferroptosis has become increasingly understood, the fully functional Nrf2 maintains cellular iron homeostasis (upregulates ferritin FTH1 and output protein FPN1), ensures antioxidant capacity (activates the System Xc-/GSH/GPX4 axis), and inhibits lipid peroxidation (downregulates ACSL4, etc.) through its transcriptional regulatory network (Zhou et al., 2024)

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Instead, it seems likely that the DMSA's effect was due to the reduction of toxic metals in the RBC, allowing glutathione to return to a normal level