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Subsequently, analysis was conducted utilizing a CytoFlex S flow cytometer (Beckman, California, USA)

10.1016/j.tplants.2009.11.009 42 SzekelyG.AbrahamE.CseploA.RigoG.ZsigmondL.CsiszrJ.et al

It reduces pro-inflammatory factors and ROS generation, and promotes HO-1 expression, suggesting its potential as an anti-inflammatory and antioxidant agent

NH2-triP is then transformed into 6-pyruvoyltetrahydrobiopterin (6-PTP) by 6-pyruvoyl tetrahydrobiopterin synthase (PTPS), and finally, 6-PTP is reduced to BH4 via three successive reactions catalyzed by sepiapterin reductase (SPR)