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The induction of stress by therapy could affect tumor cells in different ways: including the induction of autophagy, cellular senescence, apoptosis, or necrosis, all of which are, in part, interconnected, and damages induced by therapyeither chemo- or radiotherapy could induce autophagy as a housekeeping process (Kanzawa et al., 2012)

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doi: 10.1093/aje/kwi118