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In prostate cancer, aloe-emodin exhibits anti-cancer effects against DU 145 cells by inducing ROS-mediated oxidative stress, apoptosis, mitochondrial dysfunction, and inhibiting Wnt/ -catenin signaling [500]

[15] In hepatocytes, compounds undergo enzymatic transformation in two main phases: Phase I reactions (often mediated by cytochrome P450 enzymes) introduce functional groups, and Phase II reactions conjugate these compounds to increase water solubility and facilitate elimination

Differential expression patterns of growth-related microRNAs in the skeletal muscle of Nile tilapia (Oreochromis niloticus)

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