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reveal that in Bacillus cereus , thymol and carvacrol, as ingredients of OEO, can damage cellular membranes and reduce the pH gradient in the cellular membranes, resulting in proton motive force, reduced ATP pools, and cell death (Ultee et al., 2002)

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Furthermore, it should be noted that three recently discovered dimeric indole alkaloids namely 17-deacetoxycyclovinblastine, 14,15-didehydrocyclovinblastine, and 17-deacetoxyvinamidine along with five established compounds (vinamidine, leurosine, catharine, cycloleurosine, and leurosidine) exhibited in vitro viability inhibition against the human breast cancer cell line MDA-MB-231 with an inhibitory concentration ranging from 0.73 to 10.67 M (44)