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MPV17 mutation also disrupted its interactions with ATP synthase, MICOS, Cyclophilin D, and glucose-regulated protein 75 (GRP75)

Subsequent western blot experiments revealed that overexpression of miR-221 led to downregulation of phosphorylated MEK and ERK levels in DPCs, while knockout of miR-221 resulted in their upregulation, with no significant changes observed in the total protein amount of MEK and ERK

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Epithalon Peptide and Oxidative Stress A recent study suggested that Epithalon might reduce intracellular reactive oxygen species (ROS) levels in aged oocyte cells, potentially exhibiting antioxidative actions