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4.3.4 Barrier integrity and inflammation Chronic HPV infection disrupts the normal cervical-vaginal microbiota and mucosal metabolism, triggering persistent inflammatory signalling

doi: 10.1186/s12865-020-00355-y

Clinical Principle The clinical diagnosis of IC/BPS requires a careful history, physical examination, and laboratory examination to document basic symptoms that characterize the disorder and exclude infections and other disorders (see Figure 1: IC/BPS Diagnostic and Treatment Algorithm)

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