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Drug Interactions: A Largely Unmapped Territory BPC-157 has documented pharmacodynamic interactions with at least the following drug classes in animal models: NSAIDs (it modulates COX-mediated prostaglandin pathways), corticosteroids (it has counter-regulatory effects on glucocorticoid-induced tissue atrophy), SSRIs and SNRIs (via serotonin system crosstalk), and anticoagulants (via platelet and NO pathway effects)