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The proposed mechanism is Dexs reduction of neuroinflammation: it suppresses surgery-induced microglial activation and upregulates mitophagy in the hippocampus

Nrf2 overexpression inhibited the Tat effects, reducing the intracellular ROS and increasing intracellular levels of GSH [28]

Fatty acid metabolism, synthesis, and storage are affected by HS and ctl-2(ua90)II mutation One of the most important processes taking place in the peroxisomes is oxidation of very long fatty acids, products of which are stored as a reserve energy supply or shuttled to mitochondria to be fully oxidized and used to produce ATP

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