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MOA: It creates massive GH spikes comparable to 10 IU of synthetic HGH

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Disclosure of interest: Nothing to disclose E-Posters - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.01 - ACUTE MANAGEMENT - Neither thrombolysis nor thrombectomy P2058 - ESOC25-1089 HYPERBARIC OXYGEN TREATMENT IMPROVES NON-ARTERITIC CENTRAL RETINAL ARTERY OCCLUSION: AN OBSERVATIONAL RETROSPECTIVE STUDY Jiangyong Min 1 , Drue Orwig 1 , Naser Haj Aissa 1 , Alan Davis 2 , Majesta Hovingh 1 , Laurel Packard 1 , Asad Ahrar 1 , Malgorzata Miller 1 , Nadeem Khan 1 , Maulik Kantawala 1 , Nabil Wees 1 , Joshua Kooistra 1 1 Corewell Health West, Michigan State University, Grand Rapids, United States, 2 Michigan State University College of Human Medicine, Michigan State University, Grand Rapids, United States Background and Aims: Central Retinal Artery Occlusion (CRAO) is a medical emergency with currently no guideline-endorsed treatment

This condition disrupts cellular homeostasis and contributes to cellular injury and death, a process commonly referred to as lipotoxicity ( The primary mechanism underlying renal injury associated with lipid overload appears to involve OS, but it is also closely linked to ER stress, defective autophagy, and inflammatory responses ( Lactate accumulation may further amplify glycolytic activity by stabilizing HIF-1, thereby creating a positive feedback loop that exacerbates mitochondrial dysfunction and cellular damage