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This synthetic peptide consists of the C-terminal fragment (amino acids 176-191) of human growth hormone with an additional tyrosine residue at the N-terminus, designed to retain the lipolytic properties of growth hormone while avoiding its growth-promoting effects

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In this work, we identify a conserved set of genes activated by mitochondrial translation inhibition and establish C32E8.9 as essential for the resulting healthspan and lifespan extension in C