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4.4 Clinical trials: reproductive and metabolic outcomes of MI in PCOS Across randomized trials and meta-analyses, MI consistently signals benefit for reproductive endpoints in PCOS, though the magnitude varies with phenotype, baseline IR, and treatment context (143, 148)

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The only exception is the mitochondria present in the heart of rat.33 This implies that the breakdown of hydrogen peroxide to water and oxygen is carried out by another enzyme known as glutathione peroxidase in mammalian cell mitochondria

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