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Senescence and pre-malignancy: How do tumors progress

N Engl J Med 344:424429 Brigelius-Floh R, Floh L (2020) Regulatory phenomena in the glutathione peroxidase superfamily

We examined BAL cells as the inflammatory response is aberrant in sarcoidosis with (a) yet unknown antigen(s) triggering an exuberant although dysfunctional immune response with CD4 + T cells, Tregs, high levels of Th1 cytokines TNF-, IFN, and IL-2 10,33,34 , along with inappropriate counter regulatory responses