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Genetic ablation and/or pharmacological inhibition of FABP5 ameliorate the HCC burden in mice

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Recent studies have demonstrated an important link between the gut microbiota and the onset and progression of several immune diseases in humans, emphasizing that gut microbiota-derived metabolites play a non-negligible role in autoimmune diseases

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These changes reduce binding affinity for the IGF binding proteins (IGFBPs), which extends free, bioavailable IGF-1 in research systems

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