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Methods Human specimens All human liver tissues used in this study were obtained after informed consent was obtained from patients undergoing operations at either the Department of Visceral, Thoracic and Vascular Surgery (VTG), University Hospital Carl Gustav Carus Dresden (UKD) or Leipzig University Medical Center

Generally, roGFP probes are appropriate for measuring the thiol/disulfide equilibrium within a linear range of about 30 mV from their midpoint potential equivalent to an OxD between 10 and 90%