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Clinically, metformin has been shown to mitigate the risk of CVD in diabetic patients, while preclinical studies have demonstrated its efficacy in enhancing cognitive function in AD murine models

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To reduce this effect, we pre-treated HCT116 cells with NAC for 24 h, and then replaced the medium for NAC-free medium containing FA

Treatment may include whole-bowel irrigation with polyethylene glycol electrolyte solution if radiographic evidence of retained metal (toys, coins, paint chips) is present