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It could be helpful for dogs with inflammatory conditions of the gut, such as inflammatory bowel disease (IBD)

They are required for embryonic development, and are produced mainly in the liver in response to a hepatocyte growth hormone

Coronary atherosclerosis initiates with endothelial damage to the vascular intima, followed by a sequence of events including lipid deposition, vascular smooth muscle cell proliferation, and extracellular matrix synthesis, collectively resulting in arterial wall thickening and progressive luminal narrowing (17)