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Infections typically exhibit a notable presence of CD4+/CD25 + regulatory T cells, activated T helper 2 (Th2) cells, and suppression of cytotoxic function, resulting in T cell anergy (Koskela et al., 2000)

Studies also demonstrate that ketones, which are biomarkers of the brains aging response to fuel sources, increase the stability of brain networks, while decreasing glucose, affecting overall brain activity (33)

In atherosclerotic blood vessels, impaired mitophagy within endothelial and smooth muscle cells incites inflammatory activation and phenotypic transformation

Autoimmune diseases like lupus and rheumatoid arthritis, along with chronic kidney, liver, and thyroid conditions, may also lead to neuropathy