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GH- , ( ) , - : , , 1015 : GHS-R1a IGF-1

Mechanistically, these effects appeared to be mediated through mitochondrial uncoupling, AMPK activation, modulation of mTOR and PPAR signaling, improved mitochondrial bioenergetics, antioxidant defense and global metabolic reprogramming (Fig

An analysis of CRGs demonstrated the prognostic value of these genes, especially LIPT1, in melanoma and the correlation between LIPT1 expression with immune infiltration [65]