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Occasional reports of headache, dizziness, or nausea, typically mild and transient

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Anupam Bishayee, Seyed Mohammad Nabavi, Stphane Zingue, and Roja Rahimi reviewed and revised the manuscript

Active site loop architecture is important in the efficient processing of small glucuronide substrates To explain the range of catalytic efficiencies exhibited by our panel of GUS enzymes, particularly the poor processing activity demonstrated by the new L1 GUS enzymes, we manually docked p NPG into the active site of each GUS enzyme (Figs 4 and 5)