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At normal body temperature, the half-life of the enzyme is shorter than normal, leading to a decrease in fatty acid beta-oxidation and ATP generation

In addition, we suggest that selenium deficiency enhances susceptibility to ferroptotic processes, as well as other programmed cell death pathways due to a reduction in GPx4 activity

It has been reported that BNIP3-mediated mitophagy is crucial for regulation hepatic lipid metabolism and may protect against NAFLD progression [194]

Clinical literature documents anaphylaxis cases following parenteral vitamin B-12 administration, particularly with cyanocobalamin formulations