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Perreira Barreto L, de Oliveira Silva RY, de Almeida BB, Payo Ovdio P, Jordao AA

PEDF is only highly expressed in undifferentiated human retinal cells, like Y79 retinoblastoma cells, but is either absent or down-regulated in their differentiated counterparts

Although MLM production was significantly improved through exploitation of the substrate preferences of endogenous acyltransferases and optimization of culture conditions, the overall yield of MLM remains relatively low